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Mostly, kidney complications occur after long-term administration of anabolic-androgenic steroids. These investigators performed a systematic review and meta-analysis of controlled trials of androgen adjuvants (testosterone, dehydroepiandrostereone) and the androgen-modulating agent (letrozole) in poor responders undergoing IVF treatment. In castrated rats, BMS564929 demonstrated tissue selectivity and potent suppression of luteinizing hormone.
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